Controlling Microbes with Drugs - History Page

	Date/Time	Made By	Edit Note	Type	Scope
	Jun 23 2009, 5:16 PM EDT	flattail	Moved from: Chapter Notes	move	No content added or deleted.
Change: Moved by flattail Jun 23 2009, 5:16 PM EDT
	Jun 23 2009, 5:15 PM EDT	flattail	Rename	rename	No content added or deleted.
Change: Renamed from Chapter 12 by flattail Jun 23 2009, 5:15 PM EDT for: Rename
	Apr 27 2009, 11:44 PM EDT	MandaF		edit
Change: There were only format changes (bold, italics, etc.) in this version. See this version for details. (Word count: 2649)
	Apr 8 2009, 7:45 PM EDT	connieodessa		edit	6 words added 5 words deleted
Change: inon he retrieved them. It was then that he saw a zone around the invading puss where bacteria could not seem to grow. He continued to isolate anand extract formfrom moldy bread and was able to identify it as being Pennicillium.Penicillin. He began View changes from previous version. (Word count: 2649)
	Mar 30 2009, 2:28 AM EDT	ambergoose	Adding "test yourself" questions	edit	207 words added 9 words deleted
Change: Most of these drugs are active only in young, growing cells - old, inactive, or dormant cells don't synethize peptidoglycan. • Penicillins do not penetrate the outer membrane and are less effective against gram-negative bacteria.• Broad spectrumBroad-spectrum penicillins and cephalosporins can cross the cell walls of gram-negative bacteria. View changes from previous version. (Word count: 2649)
	Mar 30 2009, 2:15 AM EDT	ambergoose	downsizing font	edit	6 words added 7 words deleted 1 image added 1 image deleted
Change: gram negativegram-negative rods like Escherichia, Psuedomonas, Salmonella, Shigella.Tetracycline antibiotics- Semisynthetics derived from a species of Streptomyces. Blocks protein synthesis, effective against a wide variety of bacteria. Used to treat several types of STD's as well as Rocky Mt Spotted Fever, Lyme Disease, typhus, cholera, acne. Side View changes from previous version. (Word count: 2460)
	Mar 26 2009, 5:03 PM EDT	SaraE.	chpter 12 add questions	edit	27 words added
Change: pain. The most appropriate treatment is:a. penicillin.b. chloroquine.c. anti-inflammatory drugs. d. rifampin.e. no treatment. 22. Some of the benifits of interferon are:a. reduce the time in healingb. preventing some symptomsc. slowing the progress.d. all of the above. View changes from previous version. (Word count: 2461)
	Mar 26 2009, 3:33 PM EDT	emmaevans		edit	2 words deleted 2 images added 1 image deleted
Change: Alexander FlemingAlexander Fleming:In 1928 he was studying staphylococci. He was already known as a great researcher, but also as a careless lab technician. After being View changes from previous version. (Word count: 2434)
	Mar 26 2009, 3:28 PM EDT	emmaevans		edit	22 words added 2 words deleted
Change: These drugs will have "cef, ceph, or kef" in thier names. Most are given parentally, but some are given orally. Aminoglycosides- Is made from Streptomyces (filamentous fungi-like soil bacteria.) Relatively broad spectrum because they inhibit protein synthesis. Streptomycin & gentamicin are newer and View changes from previous version. (Word count: 2436)
	Mar 26 2009, 3:25 PM EDT	emmaevans		edit	21 words added
Change: Any woman taking a Tetracycline antibiotic would also be on some sort of birth control. Tetracycline can cause severe birth defects. Chloramphenicol- Is a Streptomyces antibiotic, is a broad-spectrum, also blocks protein synthesis. Very toxic and only used when other options are not available. New classes- Always View changes from previous version. (Word count: 2416)
	Mar 26 2009, 3:21 PM EDT	emmaevans		edit	1 word added 1 word deleted
Change: gram-negativegram-positive bacteria. Semisythetic penicillin's (Ampicillin, carbenicillin, and amoxicillin): Have a broader spectrum.Alexander FlemingAlexander Fleming:In 1928 he was studying staphylococci. He was already known as a great researcher, but also View changes from previous version. (Word count: 2395)
	Mar 26 2009, 3:19 PM EDT	emmaevans	Alexander Fleming	edit	163 words added
Change: In 1928 he was studying staphylococci. He was already known as a great researcher, but also as a careless lab technician. After being away he View changes from previous version. (Word count: 2395)
	Mar 26 2009, 12:05 AM EDT	ambergoose	cleaning up page	edit	21 words added 18 words deleted
Change: was the first Penicillinpenicillin wasthat became the patent for all other "cillins""cillins":a. Vb. Gc. Ad. C16. The adverse effect of tetracycline given to young children is...a. allergies b. joint damagec. discoloration of teethd. dependency on drug17. Which View changes from previous version. (Word count: 2231)
	Mar 25 2009, 7:58 PM EDT	KeLsLynn		edit	2 words added 1 image added
Change: Alexander FlemingCephalosporins- Relatively new, but are the most commonly administered group of antibiotics. Produced from the mold Cephalosporium. Similar in structure and function of penicillins, but have a few advantages like: relatively large spectrum, View changes from previous version. (Word count: 2229)
	Mar 24 2009, 3:58 PM EDT	kabney	kcabney edit questions	edit	33 words added
Change: a. weakining the worms so they can be flushed out by the intestineb. infibiting worm metabolismc. blocking the absorption of nutrientsd. inhibiting egg production21. A patient has a red circular rash on his arm and fever, malaise, and joint pain. The most appropriate treatment isa. View changes from previous version. (Word count: 2227)
	Mar 24 2009, 3:51 PM EDT	kabney	kcabney question # 20	edit	33 words added
Change: d.tetracycline 19. Yogurt has been shoen to control_________.a. alergiesb. fungusc. E.colid. staphylococcus 20. A patient has a red circular rash on his arm and fever, malaise, and joint pain. The most appropriate treatment isa. penicillin.b. chloroquine.c. anti-inflammatory drugs. d. rifampin.e. no treatment. View changes from previous version. (Word count: 2194)
	Mar 23 2009, 9:42 PM EDT	SaraE.	chptr 12 questions 18 & 19	edit	24 words added 82 words deleted
Change: wallto arecontrol_________.a. quinolonesalergiesb. beta-lactamsfungusc. tetracyclinesE.colid. aminoglycosides20. Most antihelminthic drugs function bystaphylococcusa. weakening the worms so they can be flushed out by the intestineb. inhibiting worm20. metabolismc. blocking the absorption of nutrientsd. inhibiting egg production View changes from previous version. (Word count: 2160)
	Mar 23 2009, 6:56 PM EDT	emilylloyd		edit	27 words added 43 words deleted
Change: 2. Inhibition of nucleic acid synthesis, structure or function3. Inhibition of protein synthesis4. Disruption of cell membrane structure or function5. Disruption of metabolic pathway1.DrugsDrugs that affect the bacterial cell wall • Most bacterial cell walls contain a rigid girdle of peptidoglycan.• Penicillin View changes from previous version. (Word count: 2215)
	Mar 23 2009, 6:40 PM EDT	emilylloyd	new definitions	edit	209 words added 88 words deleted 2 images added 3 images deleted
Change: Side Effects: Toxic to growing teeth and bones, causes birth defects, can cause GI upset, sensitivity to sunlight, and can discolor tooth enamel. Can cause a superinfection, and should never be given to pregnant women, or children. Chloramphenicol- Is a Streptomyces antibiotics-antibiotic, Usedis againsta broad-spectrum, View changes from previous version. (Word count: 2233)
	Mar 23 2009, 2:59 PM EDT	jchilton		edit	13 words added
Change: flashcards for this chapter are at www.flashcardexchange.com under kevin youngs micro chapter 12 Questions: Q&A Page~~Home Page~~Top of Page 1. When did Sulfa "hit" the market?a. 1920'sb. 1940'sc. 1950'sd. 1930's2. During WW II which country started "rediscovering" the effects of Penicillin? View changes from previous version. (Word count: 2098)